120353-04-0Relevant articles and documents
Antagonistes calciques. I. Remplacement du groupe dimethoxy-3,4- phenylethyle du verapamil
Laguerre, M.,Boyer, C.,Carpy, A.,Panconi, E.,Cognic, F.,Vaugien, B.
, p. 351 - 359 (1990)
In the verapamil structure, the 3,4-dimethoxy phenylethyl group has been replaced by several moieties belonging to α- and β-blockers or other classes of calcium channel blockers.The best derivatives, as calcium blockers, were prepared with β-blocker fragments like aryloxypropanolamines (AOPA) with an ortho substituent on the aromatic ring.
Novel phenoxyalkylamine derivatives. IV. Synthesis, Ca2+-antagonistic activity and quantitative structure-activity analysis of α-isopropyl-α-[3-[3-(3-methoxyphenoxy)propylamino]propyl]-α-phenyl cetonitrile derivatives
Mitani,Sakurai,Suzuki,Morikawa,Koshinaka,Kato,Ito,Fujita
, p. 4103 - 4120 (2007/10/02)
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