120355-42-2 Usage
General Description
The chemical compound (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid is a complex organic molecule with a purine base and a furo[3,4-d][1,3]dioxole-4-carboxylic acid moiety. It contains a chloro-substituted purine ring and a tetrahydrofuran ring, as well as a carboxylic acid functional group. (3AS,4S,6R,6AR)-6-(6-chloro-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carboxylic acid may have potential biological activity, as purines and carboxylic acids are commonly found in biologically active molecules. Additionally, the presence of a chloro-substituted purine may suggest potential pharmacological applications, as halogenated compounds are often used in drug development due to their ability to modulate biological activity. Further research into the chemical properties and potential biological activity of this compound is warranted.
Check Digit Verification of cas no
The CAS Registry Mumber 120355-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,3,5 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 120355-42:
(8*1)+(7*2)+(6*0)+(5*3)+(4*5)+(3*5)+(2*4)+(1*2)=82
82 % 10 = 2
So 120355-42-2 is a valid CAS Registry Number.
120355-42-2Relevant articles and documents
RUTHENIUM TETRAOXIDE: A MILD REAGENT FOR THE OXIDATION OF 2',3'-O-ISOPROPYLIDENE PURINE NUCLEOSIDES
Singh, Ambarish K.,Varma, Rajender S.
, p. 2307 - 2310 (1992)
2',3'-O-Isopropylidene purine nucleosides have been oxidized with ruthenium tetraoxide to provide the corresponding 5'-carboxylic acids in quantitative yields under neutral conditions.
SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5
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Paragraph 00505-00506, (2020/10/20)
The disclosure is directed to methods of treating disease using compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI:
SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5)
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Paragraph 00511, (2018/09/12)
The disclosure is directed to compounds of Formula I, Formula II, Formula III, Formula IV, Formula V, or Formula VI: Methods of their use in inhibiting a protein arginine methyltransferase 5 (PRMT5) enzyme and treating disease, as well as methods of their preparation are also described.
