1203589-45-0Relevant articles and documents
Synthesis of 3-Benzylphthalide Derivatives by Using a TDAE Strategy
Ibrahimi, Maroua,Khoumeri, Omar,Abderrahim, Raoudha,Terme, Thierry,Vanelle, Patrice
, p. 283 - 286 (2020/11/23)
A one-pot synthesis of new 3-benzylphthalide derivatives was developed by using a strategy based on tetrakis(dimethylamino)ethylene (TDAE). The reactions in the presence of TDAE of substituted benzyl chlorides with methyl 2-formylbenzoate or of substitute
Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
Li, Tianlei,Li, Jishun,Zhu, Zihao,Pan, Weidong,Wu, Song
, p. 20879 - 20883 (2019/07/12)
A cobalt-catalyzed C(sp3)-H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarenes. Notably, TFA/TFAA was used for the first time as a mixed solvent in cobalt-catalyzed oxygenation of benzylic methylenes.
HALO-SUBSTITUTED PIPERIDINES AS OREXIN RECEPTOR MODULATORS
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Page/Page column 115, (2017/09/05)
The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.