1203809-99-7Relevant academic research and scientific papers
Synthesis and biological evaluation of 2-amino-7,7-dimethyl 4-substituted-5-oxo-1-(3,4,5-trimethoxy)-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile derivatives as potential cytotoxic agents
Alqasoumi, Saleh I.,Al-Taweel, Areej M.,Alafeefy, Ahmed M.,Hamed, Mostafa M.,Noaman, Eman,Ghorab, Mostafa M.
supporting information; experimental part, p. 6939 - 6942 (2010/08/04)
A large number of antimitotic drugs, derived from natural sources or chemically synthesized, have been identified and shown to interfere with the tubulin system. Inhibition of tubulin polymerization is among the important targets useful in the cancer ther
