1204008-34-3Relevant academic research and scientific papers
Bis-4-aminobenzamidines: Versatile, fluorogenic A/T-selective dsDNA binders
Vazquez, Olalla,Sanchez, Mateo I.,Martinez-Costas, Jose,Vazquez, M. Eugenlo,Mascarenas, Jose L.
, p. 216 - 219 (2010)
(Figure presented) N1, N3-Bls(4-amldlnophenyl) propane-1, 3-dlamlne (BAPPA, R = H) Is a blsamlnobenzamldlne fluorogenlc derivative that displays a large Increase In Its emission fluorescence when bound to the minor groove of specific A/T DNA sites (Kd for an AATT site ～ 79 ± 6 nM). Moreover, the structural characteristics of BAPPA allow the easy Introduction of functional groups that protrude out of the DNA surface.
