1204035-59-5

Basic information

• Product Name: (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride
• Synonyms: (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride
• CAS NO: 1204035-59-5
• Molecular Weight: 360.264
• Mol File: 1204035-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride(1204035-59-5)
• EPA Substance Registry System: (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride(1204035-59-5)

Safety Data

• Hazardous Substances Data: 1204035-59-5(Hazardous Substances Data)

Upstream product

• 1204181-48-5 (S)-tert-butyl 1-(5-chloro-2-formylphenyl)pyrrolidin-3-ylcarbamate 
• 1204035-60-8 (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate 

Relevant articles and documents

CHEMICAL COMPOUNDS 251

The invention relates to chemical compounds of formula (I), and salts thereof. In some embodiments, the invention relates to inhibitors or modulators of PIM-1 and/or PIM-2, and/or PIM-3 protein kinase activity or enzyme function. In still further embodiments, the invention relates to pharmaceutical compositions comprising compounds disclosed herein, and their use in the prevention and treatment of PIM kinase related conditions and diseases, preferably cancer.