1204035-60-8

Basic information

• Product Name: (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate
• Synonyms: (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate
• CAS NO: 1204035-60-8
• Molecular Weight: 423.92
• Mol File: 1204035-60-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate(1204035-60-8)
• EPA Substance Registry System: (S,Z)-tert-butyl 1-(5-chloro-2-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)pyrrolidin-3-ylcarbamate(1204035-60-8)

Safety Data

• Hazardous Substances Data: 1204035-60-8(Hazardous Substances Data)

Upstream product

• 61072-56-8 4-chloro-2-fluorobenzaldehyde 
• 122536-76-9 3(S)-(tert-butoxycarbonylamino)pyrrolidine 
• 2295-31-0 thiazoline-2,4-dione 
• 1204181-48-5 (S)-tert-butyl 1-(5-chloro-2-formylphenyl)pyrrolidin-3-ylcarbamate 

Downstream Products

• 1204035-59-5 (S,Z)-5-(2-(3-aminopyrrolidin-1-yl)-4-chlorobenzylidene)thiazolidine-2,4-dione hydrochloride 

Relevant articles and documents

Discovery of novel benzylidene-1,3-thiazolidine-2,4-diones as potent and selective inhibitors of the PIM-1, PIM-2, and PIM-3 protein kinases

Novel substituted benzylidene-1,3-thiazolidine-2,4-diones (TZDs) have been identified as potent and highly selective inhibitors of the PIM kinases. The synthesis and SAR of these compounds are described, along with X-ray crystallographic, anti-proliferati