1204295-63-5

Basic information

• Product Name: 2-Chloro-4-(1,1-difluoroethyl)pyridine
• Synonyms: 2-Chloro-4-(1,1-difluoroethyl)pyridine
• CAS NO: 1204295-63-5
• Molecular Formula: C7H6ClF2N
• Molecular Weight: 177.5790464
• Product Categories: Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles;Pyridines
• Mol File: 1204295-63-5.mol
• Article Data: 9

Chemical Properties

• Flash Point: 93°C
• Appearance: /
• Density: 1.305g/mLat 25℃
• Refractive Index: n20/D 1.481
• CAS DataBase Reference: 2-Chloro-4-(1,1-difluoroethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-(1,1-difluoroethyl)pyridine(1204295-63-5)
• EPA Substance Registry System: 2-Chloro-4-(1,1-difluoroethyl)pyridine(1204295-63-5)

Safety Data

• Hazard Codes: T
• Statements: 25-36/37/38
• Safety Statements: 26-45
• RIDADR: UN 2810 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 1204295-63-5(Hazardous Substances Data)

Upstream product

• 23794-15-2 1-(2-chloropyridin-4-yl)ethan-1-one 

Relevant articles and documents

Scalable Approach to Fluorinated Heterocycles with Sulfur Tetrafluoride (SF4)

A general approach to fluorinated (hetero)aromatic derivatives is elaborated. The key reaction is a deoxofluorination of substituted acetophenones with sulfur tetrafluoride (SF4). In contrast to previous deoxofluorination methods, this transformation is fast, scalable (up to 70 g), and high-yielding. More than 100 novel or previously hardly accessible fluorinated heterocycles, interesting for medicinal chemistry and agrochemistry, were synthesized.

CYCLOPROPANECARBOXAMIDO-SUBSTITUTE AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS

Provided are cyclopropanecarboxamido-substituted aromatic compounds that inhibit protein kinases and their use in anti-tumor area. In particular, tyrosine-kinase inhibitors and Raf-kinase inhibitors as anti-tumor agents, their preparation, pharmaceutical composition, and their use in the treatment of cancer are also provided.

PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES

The invention relates to pyrrolone compounds of the formula (I) wherein X, R1, R2, R3 and A are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.