1204307-23-2Relevant academic research and scientific papers
Enantioselective synthesis of 3,4-dihydroisoquinolin-1(2H)-ones by nickel-catalyzed denitrogenative annulation of 1,2,3-benzotriazin-4(3H)-ones with allenes
Yamauchi, Motoshi,Morimoto, Masao,Miura, Tomoya,Murakami, Masahiro
supporting information; experimental part, p. 54 - 55 (2010/03/25)
(Chemical Equation Presented) A denitrogenative annulation reaction of 1,2,3-benzotriazin-4(3H)-ones with allenes catalyzed by a nickel-phosphine complex to produce a variety of substituted 3,4-dihydroisoquinolin-1(2H)-ones in a regioselective manner is described. A highly enantioselective version, as well as structural evidence for the mechanistic course of this reaction, is also presented.
