107559-07-9

Usage

Chemical classification

Benzotriazinone

Physical appearance

White to off-white solid

Usage

Building block for the synthesis of various pharmaceuticals and agrochemicals

Chemical structure

Contains a benzotriazole ring system with a 3-(2-methoxyphenyl) substituent

Unique properties

The presence of the 3-(2-methoxyphenyl) substituent gives it unique properties and applications

Pharmacological activities

Known for its potential pharmacological activities

Therapeutic benefits

Being studied for its potential therapeutic benefits in various medical treatments and drug development

Safety protocols

Important to handle with care and follow proper safety protocols when working with it in a laboratory setting
Please note that this list is based on the information provided in the material and may not be exhaustive. It is always recommended to consult a reliable source or expert for more detailed information on a specific chemical compound.

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 134-20-3 2-carbomethoxyaniline 
• 70083-21-5 2-amino-N-(2-methoxyphenyl)benzamide 
• 111475-27-5 2-[3-(2-methoxy-phenyl)-triazenyl]-benzoic acid methyl ester 

Downstream Products

• 1204307-23-2 C₂₃H₂₇NO₂ 
• 1268883-55-1 C₂₃H₂₀N₂O₂ 

Relevant academic research and scientific papers

Nickel-Catalyzed Denitrogenative Annulation of 1,2,3-Benzotriazin-4-(3H)-ones with Benzynes for Construction of Phenanthridinone Scaffolds

The synthesis of phenanthridinones via denitrogenative annulation of 1,2,3-benzotriazin-4-(3H)-ones with arynes catalysed by Ni(0)/dppm was successfully developed. A variety of phenanthridinones were prepared in good to excellent yields. Based on this method, nature product, N-methylcrinasidine, was synthesized. (Figure presented.).

Saccharin and tert-Butyl Nitrite: Cheap and Efficient Reagents for the Synthesis of 1,2,3-Benzotriazine-4-(3H)-ones from 2-Aminobenzamides under Metal-Free Conditions

A mild and eco-friendly protocol for the synthesis of 1,2,3-benzotriazine-4-(3H)-ones is described using saccharin as a cheap and efficient catalyst and tert-butyl nitrite as a diazotization reagent for the first time. The current method has advantages su

Preparation method of N-substituted 1,2,3-phentriazine-4-ketone

The invention discloses a preparation method of N-substituted 1,2,3-phentriazine-4-ketone. The preparation method specifically comprises the following step: by taking anthranilamide as a reaction substrate, taking tert-butyl nitrite as a nitrogen source a

Mild and efficient TBAI-catalyzed synthesis of 1,2,3-benzotriazine-4-(3H)-ones from tert-butyl nitrite and 2-aminobenzamides under acid-free conditions

A facile and efficient annulation of 2-aminobenzamides and tert-butyl nitrite was developed, affording 1,2,3-benzotriazine-4-(3H)-ones in good yields under mild conditions. Notably, the reaction was carried out in the absence of strong acid and tert-butyl

Potassium Iodide/tert-Butyl Hydroperoxide-Mediated Oxidative Annulation for the Selective Synthesis of N-Substituted 1,2,3-Benzotriazine-4(3H)-ones Using Nitromethane as the Nitrogen Synthon

A novel and efficient oxidative annulation of 2-aminobenzamides with nitromethane has been developed for the chemoselective synthesis of N-substituted 1,2,3-benzotriazine-4(3H)-ones in moderate to excellent yields under transition metal-free conditions. T

Steric effects in the base-catalyzed cyclization of 1-[2-(methoxycarbonyl)phenyl]-3-(2-substituted phenyl)triazenes

Eleven model 1-[2-(methoxycarbonyl)phenyl]-3-(2-substituted phenyl)triazenes were synthesized and their cyclization kinetics examined in aqueous-methanolic buffer solutions (51 wt.% methanol) at various pH values. 3(2-Substituted phenyl)benzo[d][1,2,3]tri