1204334-26-8

Basic information

• Product Name: 7-BROMOQUINOLINE-2-CARBONITRILE
• Synonyms: 7-BROMOQUINOLINE-2-CARBONITRILE
• CAS NO: 1204334-26-8
• Molecular Formula: C10H5BrN2
• Molecular Weight: 233.06
• Mol File: 1204334-26-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-BROMOQUINOLINE-2-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-BROMOQUINOLINE-2-CARBONITRILE(1204334-26-8)
• EPA Substance Registry System: 7-BROMOQUINOLINE-2-CARBONITRILE(1204334-26-8)

Safety Data

• Hazardous Substances Data: 1204334-26-8(Hazardous Substances Data)

Upstream product

• 4965-36-0 7-bromoquinoline 
• 860720-24-7 7-bromoquinoline 1-oxide 
• 7677-24-9 trimethylsilyl cyanide 

Relevant articles and documents

Hypervalent Iodine(III)-Mediated Regioselective Cyanation of Quinoline N-Oxides with Trimethylsilyl Cyanide

A regioselective cyanation of quinoline N-oxides with trimethylsilyl cyanide was developed by using (Diacetoxyiodo) benzene (PIDA) as mediated hypervalent iodine(III) reagent under metal-free and base-free reaction conditions to obtain 2-cyanoquinolines. The efficient PIDA reagent could play the role of an activator of the substrates and an accelerator of N?O bond cleavage. The reaction system featured a wide range of substrate suitability and high yields. The procedure was enlarged gram-scale to synthesize the tuberculosis (TB) inhibitor. Finally, according to some experimental results, a plausible mechanism for the cyanation reaction is proposed. (Figure presented.).