120442-16-2

Upstream product

• 55708-75-3 3-Acetoxy-4-((R)-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-benzoic acid 
• 288299-07-0 3-Hydroxy-4-((R)-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-benzoic acid ethyl ester 
• 13226-18-1 (R)-(-)-Cinenic acid 
• 29171-20-8 3,7-dimethyloct-6-en-1-yn-3-ol 
• 288299-04-7 (E)-3-((R)-2,6,6-Trimethyl-tetrahydro-pyran-2-yl)-acrylic acid ethyl ester 
• 288299-06-9 2-[(E)-3-((R)-2,6,6-Trimethyl-tetrahydro-pyran-2-yl)-prop-2-en-(E)-ylidene]-succinic acid 1-ethyl ester 
• 63023-52-9 5-Methyl-2-((R)-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-phenol 
• 120342-22-5 (R)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-phenyl]-6-methyl-hept-6-en-2-ol 
• 63023-53-0 Acetic acid 5-methyl-2-((R)-2,6,6-trimethyl-tetrahydro-pyran-2-yl)-phenyl ester 
• 120342-19-0 (S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-phenyl]-1-p-tolylsulfanyl-propan-2-ol 
• 120342-16-7 (S)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-4-methyl-phenyl]-1-((R)-toluene-4-sulfinyl)-propan-2-ol 
• 120342-20-3 tert-Butyl-dimethyl-[5-methyl-2-((S)-2-methyl-oxiranyl)-phenoxy]-silane 
• 120342-11-2 (R)-(2-t-butyldimethylsilyloxy-4-methyl)phenyl (p-tolylsulfinyl)methyl ketone 
• 13226-32-9 (R)-(-)-Cinenic acid methyl ester 

Relevant academic research and scientific papers

Bisabolane sesquiterpenes: Synthesis of (R)-(+)-sydowic acid and (R)- (+)curcumene ether

A stereoselective synthesis of (R)-(+)-sydowic acid 1 and (R)-(-)- curcumene ether 2 is described. The enantiomerically pure tetrahydropyran building block (R)-(-)-cinenic acid 5 is obtained by resolution of the racemic acid. The aromatic moiety is constructed using a benzoannulation reaction as a key step. An easy way to the title compounds in racemic form is also reported.

Diastereofacial Control in the Reaction of (R)-α-(p-Tolylsulfinyl)acetophenones with Several Organometallics

The diastereofacial controlled addition of organometallics to optically active β-ketosulfoxide was achieved to furnish both diastereomers of β-hydroxy sulfoxide depending on the selection of organometallic reagents.Trichloromethyltitanium added to (R)-α-(