1204535-20-5

Basic information

• Product Name: 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile
• Synonyms: 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile
• CAS NO: 1204535-20-5
• Molecular Weight: 279.363
• Mol File: 1204535-20-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile(1204535-20-5)
• EPA Substance Registry System: 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile(1204535-20-5)

Safety Data

• Hazardous Substances Data: 1204535-20-5(Hazardous Substances Data)

Upstream product

• 1251110-16-3 4-cyano-2-methylbenzenesulfonyl chloride 
• 78881-21-7 4-amino-3-methylbenzonitrile 
• 583-75-5 4-Bromo-2-methylaniline 
• 1204535-19-2 1,1-dimethylethyl (2S)-4-[(4-cyano-2-methylphenyl)sulfonyl]-2-methyl-1-piperazinecarboxylate 

Downstream Products

• 1204535-63-6 3-Methyl-4-({(3S)-3-methyl-4-[(6-methyl-3-pyridinyl)carbonyl]-1-piperazinyl}sulfonyl)benzonitrile 
• 1204925-59-6 3-Methyl-4-{[(3S)-3-methyl-4-(pyrazolo[1,5-a]pyrimidin-3-ylcarbonyl)-1-piperazinyl]sulfonyl}benzonitrile 
• 1204925-68-7 4-({(3S)-4-[(6-fluoropyrazolo[1,5-a]pyrimidin-3-yl)carbonyl]-3-methyl-1-piperazinyl}sulfonyl)-3-methylbenzonitrile 
• 1204535-72-7 4-({(3S)-4-[(6-Chloro-2-methyl-3-pyridinyl)carbonyl]-3-methyl-1-piperazinyl}sulfonyl)-3-methylbenzonitrile 
• 1204535-97-6 4-({(3S)-4-[(6-iodo-3-pyridinyl)carbonyl]-3-methyl-1-piperazinyl}sulfonyl)-3-methylbenzonitrile 

Relevant articles and documents

PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS

The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial and to treat diseases for which blocking the Cav2.2 and Cav3.2 calcium channels is beneficial, e.g. to treat pain.

Novel Derivatives

The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.