1204535-19-2

Upstream product

• 78881-21-7 4-amino-3-methylbenzonitrile 
• 1251110-16-3 4-cyano-2-methylbenzenesulfonyl chloride 
• 169447-70-5 (S)-2-methyl-piperazine-1-carboxylic acid tert-butyl ester 
• 583-75-5 4-Bromo-2-methylaniline 
• 557-21-1 zinc(II) cyanide 
• 1204535-18-1 1,1-dimethylethyl (2S)-4-[(4-bromo-2-methylphenyl)sulfonyl]-2-methyl-1-piperazinecarboxylate 

Downstream Products

• 1204535-20-5 3-methyl-4-{[(3S)-3-methyl-1-piperazinyl]sulfonyl}benzonitrile 

Relevant academic research and scientific papers

PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS

The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial and to treat diseases for which blocking the Cav2.2 and Cav3.2 calcium channels is beneficial, e.g. to treat pain.

PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS

The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial and to treat diseases for which blocking the Cav2.2 and Cav3.2 calcium channels is beneficial, e.g. to treat pain.

Novel Derivatives

The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.

Novel Derivatives

The present invention relates to novel piperazine derivatives; to processes for their preparation; to pharmaceutical compositions containing the derivatives; and to the use of the derivatives in therapy to treat diseases for which blocking the Cav2.2 calcium channels is beneficial.