120454-32-2Relevant academic research and scientific papers
PAN-ANTAGONISTS FOR THE ANDROGEN RECEPTOR AND ANDROGEN RECEPTOR MUTANTS ASSOCIATED WITH ANTI-ANDROGEN WITHDRAWAL
-
Page/Page column 29, (2008/06/13)
Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriat
Circumventing anti-androgen resistance by molecular design
McGinley, Paula L.,Koh, John T.
, p. 3822 - 3823 (2007/10/03)
Nuclear/steroid hormone receptors (NHRs) function as ligand-dependent transcriptional regulators of diverse sets of genes involved in development and homeostasis. Mutations to the androgen receptor (AR), a member of NHRs, have been linked to the failure o
Thermal Interconversion and Cyclisation Reactions of 2-(Arylthio)benzyl Radicals and 2-(Benzyl)thiophenoxyl Radicals
Cadogan, J. I. G.,Hutchison, H. Susan,McNab, Hamish
, p. 2875 - 2880 (2007/10/02)
Generation of the title radicals by flash vacuum pyrolysis leads to thioxanthene(s) as the sole significant product(s).Cyclisation takes place via an intermediate spirodienyl radical .
