120456-41-9

Upstream product

• 4815-36-5 ethyl 2-amino-4-phenyl-thiophene-3-carboxylate 
• 62-53-3 aniline 
• 14533-92-7 ethyl 2-cyano-3-phenylbut-2-enoate 
• 98-86-2 acetophenone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 1325222-67-0 ethyl 2-isothiocyanato-4-phenyl-5-(phenylazo)thiophene-3-carboxylate 
• 1325222-71-6 7-phenyl-6-(phenylazo)-2-thioxo-1H-[1,3,4]thiadiazolo[3,2-a]thieno[2,3-d]pyrimidin-8(2H)-one 
• 1325222-73-8 3-amino-2-(methylthio)-5-phenyl-6-(phenylazo)thieno[2,3-d]pyrimidin-4(3H)-one 
• 1325222-75-0 3-amino-2-hydrazinyl-5-phenyl-6-(phenylazo)thieno[2,3-d]pyrimidin-4(3H)-one 
• 1325222-79-4 7-phenyl-8-(phenylazo)-1,4-dihydro-6H-thieno[2',3':4,5]-pyrimido[1,2-b][1,2,4,5]tetrazin-6-one 
• 1325222-81-8 4-amino-6-phenyl-7-(phenylazo)tetrazolo[1,5-a]thieno[3,2-e]pyrimidin-5(4H)-one 
• 1325222-77-2 6-phenyl-7-(phenylazo)tetrazolo[1,5-a]thieno[3,2-e]pyrimidin-5(4H)-one 
• 1325222-87-4 ethyl 2-(4-amino-3-phenyl-2-thioxo-2,3-dihydrothiazole-5-carboxamido)-4-phenyl-5-(phenylazo)thiophene-3-carboxylate 
• 1325222-92-1 ethyl 2-(5-imino-2,4-diphenyl-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamido)-4-phenyl-5-(phenylazo)thiophene-3-carboxylate 
• 1325222-94-3 ethyl 2-(2-oxo-2H-chromene-3-carboxamido)-4-phenyl-5-(phenylazo)thiophene-3-carboxylate 
• 1325222-65-8 3-amino-5-phenyl-6-(phenylazo)-2-thioxo-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one 
• 120456-44-2 3-Methylthio-6-oxo-1,4-diphenyl-5,6-dihydropyridazin-5-carbonitril 
• 120456-43-1 4-Phenyl-2-oxo-5-phenylhydrazon-Δ³-thiolen-3-carbonitril 

Relevant academic research and scientific papers

Part 1: Synthesis and visible absorption spectra of some new monoazo dyes derived from ethyl 2-amino-4-(4′-substitutedphenyl)thiophenes

Series of monoazo dyes from some ethyl 2-amino-4-(4′- substitutedphenyl) thiophenes were prepared and characterized. The structure of the substances was confirmed by FT-IR, 1H NMR and mass spectroscopic techniques. The relationship among the structure of the dyes, their absorption characteristics and the solvatochromic and halochromic behaviors of the dyes were investigated. Introduction of electron-accepting substituent into the diazo moiety results in large bathochromic shifts in all solvents used. The dyes exhibited positive solvatochromism and their solvatochromic properties were discussed in relation to tautomerism.

Ringtransformation of Ethyl 2-Amino-thiophene-3-carboxylates: Derivatives of Pyridones and Pyridazinones

Whereas treatment of the ethyl 5-acetyl-2-amino-4-methyl-thiophene-3-carboxylate (1) with potassium hydroxide yields the 2-hydroxy-thiophene-3-carbonitrile 4 its hydrazone 2 is converted into the 1-amino-5-mercapto-2-pyridone derivative 6.The transformation of the 2-amino-5-phenylazo-thiophene derivative 9 by potassium hydroxide yields the substituted 3-mercapto-pyridazin-6(1H)one 10, with sodium ethoxide the 5-phenylhydrazone-2-oxo-thiolen-3-carbonitrile 11 is formed.From 6 the 5-mercapto-2-pyridone derivatives 7d, e can be obtained. - Keywords: 2-Aminothiophene-3-carboxylic acid derivatives; 1-Amino-2-pyridone; 1,2-Dihydro-2-oxo-pyridine-5-thioles; Pyridazin-6(1H)-one