1204616-82-9Relevant academic research and scientific papers
Synthesis of aspergillide A via proline-catalyzed trans-to-cis isomerization of a substituted tetrahydropyran
Nagasawa, Tomohiro,Nukada, Tomoo,Kuwahara, Shigefumi
scheme or table, p. 2882 - 2888 (2011/05/13)
The transformation of a common synthetic intermediate of aspergillides B and C into aspergillide A, a cytotoxin produced by a marine-derived fungus, has been accomplished in an eleven-step sequence involving an efficient proline-catalyzed isomerization of
Enantioselective Synthesis of Aspergillide B
Nagasawa, Tomohiro,Kuwahara, Shigefumi
experimental part, p. 1893 - 1894 (2010/03/04)
The enantioselective synthesis of aspergillide B, a 14-membered macrocyclic cytotoxin, was achieved in a 49% yield via 7 steps from a synthetic intermediate of aspergillide C. The spectroscopic data and specific rotation value for the synthetic material m
