1204651-57-9

Upstream product

• 1204651-56-8 Ethyl {4-[7-amino-8-ethyl-6-(methylcarbamoyl)-5-oxo-5,8-dihydro-1,8-naphthyridin-2-yl]phenyl}acetate 
• 1092523-23-3 3-[6-chloro-2-(ethylamino)pyridin-3-yl]-2-cyano-3-hydroxy-N-methylprop-2-enamide 
• 1092523-22-2 6-chloro-2-(ethylamino)pyridine-3-carbonyl fluoride 
• 1092523-21-1 6-chloro-2-(ethylamino)pyridine-3-carboxylic acid 
• 1092523-24-4 2-amino-7-chloro-1-ethyl-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide 
• 859169-20-3 1-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 15250-46-1 ethyl (4-iodophenyl)acetate 

Downstream Products

• 1204651-88-6 2-amino-1-ethyl-N-methyl-7-{4-[2-({[4-(1-methylethyl)morpholin-3-yl]-methyl}amino)-2-oxoethyl]phenyl}-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide 
• 1204651-66-0 2-amino-1-ethyl-7-{4-[2-({[(2S,4R)-1-ethyl-4-fluoropyrrolidin-2-yl]methyl}-amino)-2-oxoethyl]phenyl}-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide 
• 1204651-65-9 C₂₀H₁₉FN₄O₃ 
• 1204651-82-0 2-amino-1-ethyl-7-{4-[2-({[(2S)-1-ethyl-4,4-difluoropyrrolidin-2-yl]methyl}-amino)-2-oxoethyl]phenyl}-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide 

Relevant academic research and scientific papers

PYRIDINOPYRIDINONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The present invention relates to pyridopyridone derivatives of formula (I): in which the variables are as defined herein, to their preparation and to their therapeutic use as inhibitors of the kinase activity of PDGF (platelet-derived growth factor) ligand receptors and possibly of FLT3 (fms-like tyrosine kinase receptor) ligand receptors.