1204705-00-9Relevant academic research and scientific papers
Asymmetric Strecker Reactions Catalyzed by Thiourea Phosphonium and Ammonium Salts
Wang, Hongyu,Wang, Kaiye,Ren, Yanfei,Li, Na,Tang, Bo,Zhao, Gang
supporting information, p. 1819 - 1824 (2017/06/09)
The application of asymmetric phase-transfer catalysis to the Strecker reaction of ketimines was realized utilizing bifunctional thiourea-phosphonium salts. The asymmetric Strecker reaction of aldimines was also realized utilizing quaternary ammonium salt
Highly enantioselective titanium-catalyzed cyanation of imines at room temperature
Seayad, Abdul Majeed,Ramalingam, Balamurugan,Yoshinaga, Kazuhiko,Nagata, Takushi,Chai, Christina L. L.
supporting information; experimental part, p. 264 - 267 (2010/03/24)
(Figure presented) A highly active and enantioselective titanium-catalyzed cyanatlon of imines at room temperature Is described. The catalyst used Is a partially hydrolyzed titanium alkoxide (PHTA) precatalyst together with a readily available N-salicyl-β-aminoalcohol ligand. Up to 98% ee was obtained with quantitative yields In 15 min of reaction time using 5 mol % of the catalyst. Various N-protecting groups such as benzyl, benzhydryl, Boc, and PMP are tolerated.
