1204733-31-2Relevant articles and documents
Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA
Rawls, Katherine A.,Therese Lang,Takeuchi, Jun,Imamura, Shinichi,Baguley, Tyler D.,Grundner, Christoph,Alber, Tom,Ellman, Jonathan A.
supporting information; experimental part, p. 6851 - 6854 (2010/06/16)
The development of low μM inhibitors of the Mycobacterium tuberculosis phosphatase PtpA is reported. The most potent of these inhibitors (Ki = 1.4 ± 0.3 μM) was found to be selective when tested against a panel of human tyrosine and dual-specif