1204821-80-6

Basic information

• Product Name: 2-chloro-N⁴-(cyclopropylbenzamide)-5-fluoropyrimidin-4-amine
• Synonyms: 2-chloro-N⁴-(cyclopropylbenzamide)-5-fluoropyrimidin-4-amine
• CAS NO: 1204821-80-6
• Molecular Weight: 306.727
• Mol File: 1204821-80-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-chloro-N⁴-(cyclopropylbenzamide)-5-fluoropyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N⁴-(cyclopropylbenzamide)-5-fluoropyrimidin-4-amine(1204821-80-6)
• EPA Substance Registry System: 2-chloro-N⁴-(cyclopropylbenzamide)-5-fluoropyrimidin-4-amine(1204821-80-6)

Safety Data

• Hazardous Substances Data: 1204821-80-6(Hazardous Substances Data)

Upstream product

• 38681-77-5 4-amino-N-cyclopropylbenzamide 
• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 

Downstream Products

• 1158838-51-7 N-cyclopropyl-4-(5-fluoro-2-(4-hydroxyphenylamino)pyrimidin-4-ylamino)benzamide 

Relevant articles and documents

BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS

Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I through IV.

A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B

The two major Aurora kinases carry out critical functions at distinct mitotic stages. Selective inhibitors of these kinases, as well as pan-Aurora inhibitors, show antitumor efficacy and are now under clinical investigation. However, the ATP-binding sites