120491-90-9

Basic information

• Product Name: Diethyl 4-iodo-2,6-pyridinedicarboxylate
• Synonyms: Diethyl 4-iodo-2,6-pyridinedicarboxylate;4-Iodopyridine-2,6-dicarboxylic acid diethyl ester;diethyl 4-iodopyridine-2,6-dicarboxylate
• CAS NO: 120491-90-9
• Molecular Formula: C₁₁H₁₂INO₄
• Molecular Weight: 349.12
• Mol File: 120491-90-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 417.2°C at 760 mmHg
• Flash Point: 206.1°C
• Appearance: /
• Density: 1.635g/cm³
• Vapor Pressure: 3.59E-07mmHg at 25°C
• Refractive Index: 1.57
• PKA: -2.10±0.10(Predicted)
• CAS DataBase Reference: Diethyl 4-iodo-2,6-pyridinedicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl 4-iodo-2,6-pyridinedicarboxylate(120491-90-9)
• EPA Substance Registry System: Diethyl 4-iodo-2,6-pyridinedicarboxylate(120491-90-9)

Safety Data

• Hazardous Substances Data: 120491-90-9(Hazardous Substances Data)

Usage

General Description

Diethyl 4-iodo-2,6-pyridinedicarboxylate is a chemical compound with the molecular formula C13H14INO4. It is commonly used as a pharmaceutical intermediate in the synthesis of various drugs and pharmaceuticals. Diethyl 4-iodo-2,6-pyridinedicarboxylate is derived from 2,6-pyridinedicarboxylic acid and is characterized by the presence of an iodine atom at the 4th position of the pyridine ring. The diethyl ester groups in the molecule make it soluble in organic solvents, making it ideal for use in organic synthesis reactions. Additionally, the presence of the ester groups also makes this compound suitable for further derivatization to create new compounds with potential bioactive properties.

InChI:InChI=1/C11H12INO4/c1-3-16-10(14)8-5-7(12)6-9(13-8)11(15)17-4-2/h5-6H,3-4H2,1-2H3

Upstream product

• 71022-75-8 4-chloropyridine-2,6-dicarbonyl dichloride 
• 499-51-4 Chelidamic acid 
• 53389-01-8 diethyl 4-chloropyridine-2,6-dicarboxylate 
• 112776-83-7 diethyl 4-bromo-2,6-pyridinedicarboxylate 

Downstream Products

• 1425509-99-4 diethyl 6,6'-((((4-((4-aminophenyl)ethynyl)pyridine-2,6-diyl)bis(methylene))bis((2-ethoxy-2-oxoethyl)azanediyl))bis(methylene))bis(4-bromopicolinate) 
• 106967-33-3 4-iodo-2,6-bis(bromomethyl)pyridine 
• 120491-91-0 2,6-bis(hydroxymethyl)-4-iodopyridine 

Relevant articles and documents

An efficient triazole-pyridine-bistetrazolate platform for highly luminescent lanthanide complexes

Two new triazole-pyridine-bistetrazolate ligands were synthesized via a versatile procedure that allows for further derivatization; their corresponding homoleptic tris-ligand nona-coordinated lanthanide complexes are highly luminescent in the solid state and in a PVA polymeric matrix with measured values for the luminescence quantum yield of 70(7) and 98(9)% for Eu III and TbIII, respectively. This journal is the Partner Organisations 2014.

NOVEL 5 OR 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES

Disclosed herein are 5 or 8-substituted imidazo[l,5-a]pyridines and pharmaceutical compositions comprising at least one such 5 or 8-substituted imidazo[l,5-a]pyridines, processes for the preparation thereof, and the use thereof in therapy. Disclosed herein are certain 5 or 8- substituted imidazo[l,5-a]pyridines that can be useful for inhibiting indoleamine 2,3- dioxygenase and/or tryptophane 2,3-dioxygenase and for treating diseases or disorders mediated thereby.