120496-27-7Relevant articles and documents
Synthesis and Biological Evaluation of S-Adenosyl-1,12-diamino-3-thio-9-azadodecane, a Multisubstrate Adduct Inhibitor of Spermine Synthase
Woster, Patrick M.,Black, Alison Y.,Duff, Keith J.,Coward, James K.,Pegg, Anthony E.
, p. 1300 - 1307 (2007/10/02)
As part of a continuing search for specific inhibitors of the enzymes involved in polyamine biosynthesis, we have designed and synthesized a multisubstrate adduct inhibitor, S-adenosyl-1,12-diamino-3-thio-9-azadodecane (AdoDATAD), in which critical portio