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1205548-00-0 Usage

Chemical Properties

Orange Brown Solid


4'-Dimethylamino 7,8-Dihydroxyflavone is a synthetic 7,8-Dihydroxyflavone derivative which promotes neurogenesis and exhibits potent antidepressant effect. The 7,8-dihydroxy groups are essential for the agonistic effect. 4'-Dimethylamino 7,8-Dihydroxyflavone displays higher TrkB agonistic activity than that of 7,8-Dihydroxyflavone (D452830).

Check Digit Verification of cas no

The CAS Registry Mumber 1205548-00-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,5,5,4 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1205548-00:
120 % 10 = 0
So 1205548-00-0 is a valid CAS Registry Number.



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017


1.1 GHS Product identifier

Product name 4'-DMA-7,8-DHF*HBr

1.2 Other means of identification

Product number -
Other names 2-(4-(dimethylamino)phenyl)-7,8-dihydroxy-4H-chromen-4-one hydrobromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1205548-00-0 SDS

1205548-00-0Downstream Products

1205548-00-0Relevant articles and documents

A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect

Liu, Xia,Chan, Chi-Bun,Jang, Sung-Wuk,Pradoldej, Sompol,Huang, Junjian,He, Kunyan,Phun, Lien H.,France, Stefan,Xiao, Ge,Jia, Yonghui,Luo, Hongbo R.,Ye, Keqiang

experimental part, p. 8274 - 8286 (2011/02/23)

7,8-Dihydroxyflavone is a recently identified small molecular tropomyosin-receptor-kinase B (TrkB) agonist. Our preliminary structural-activity relationship (SAR) study showed that the 7,8-dihydroxy groups are essential for the agonistic effect. To improv

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