1205548-03-3 Usage
Description
2-(4-(DiMethylaMino)phenyl)-7,8-diMethoxy-4H-chroMen-4-one HBr, also known as 4''-Dimethylamino 7,8-Dihydroxyflavone Dimethyl Ether, is a derivative of 7,8-Dihydroxyflavone (D452830). It is characterized by its yellow solid appearance and is known for its ability to promote neurogenesis and exhibit potent antidepressant effects.
Uses
Used in Pharmaceutical Industry:
2-(4-(DiMethylaMino)phenyl)-7,8-diMethoxy-4H-chroMen-4-one HBr is used as an active pharmaceutical ingredient for its antidepressant properties. It is particularly effective due to its promotion of neurogenesis, which can contribute to the treatment of various mental health disorders.
Used in Research Applications:
In the field of neuroscience and pharmaceutical research, 2-(4-(DiMethylaMino)phenyl)-7,8-diMethoxy-4H-chroMen-4-one HBr serves as a valuable compound for studying the mechanisms of neurogenesis and the development of novel antidepressant medications. Its potent effects make it a promising candidate for further investigation and potential clinical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1205548-03-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,5,5,4 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1205548-03:
(9*1)+(8*2)+(7*0)+(6*5)+(5*5)+(4*4)+(3*8)+(2*0)+(1*3)=123
123 % 10 = 3
So 1205548-03-3 is a valid CAS Registry Number.
1205548-03-3Relevant articles and documents
Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof
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, (2018/03/25)
Novel compounds and methods related to the activation of the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of 7,8-dihydroxyflavone or derivative thereof. Specifically, methods and comp
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect
Liu, Xia,Chan, Chi-Bun,Jang, Sung-Wuk,Pradoldej, Sompol,Huang, Junjian,He, Kunyan,Phun, Lien H.,France, Stefan,Xiao, Ge,Jia, Yonghui,Luo, Hongbo R.,Ye, Keqiang
experimental part, p. 8274 - 8286 (2011/02/23)
7,8-Dihydroxyflavone is a recently identified small molecular tropomyosin-receptor-kinase B (TrkB) agonist. Our preliminary structural-activity relationship (SAR) study showed that the 7,8-dihydroxy groups are essential for the agonistic effect. To improv
