120572-36-3Relevant academic research and scientific papers
Phosphodiesterase 4-inhibiting diazepinoindolones
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, (2008/06/13)
The present invention presents compounds that inhibit phosphodiesterase 4 having Formula (I). The present invention also provides methods of using the compounds of Formula (I) to prevent or treat asthma, atopic dermatitis, rheumatoid arthritis, inflammatory bowel disorders, pulmonary hypertension, liver injury, bone loss, septic shock, or multiple sclerosis, and to pharmaceutical compositions that contain the compounds of Formula (I).
Reactions of Cyclic Anhydrides: Part XIII - Facile Synthesis of 1,2,3,4-Tetrahydro-10H-pyridazinoquinazoline-2,10-diones
Balasubramaniyan, V.,Argade, N. P.
, p. 906 - 908 (2007/10/02)
1,2,3,4-Tetrahydro-10H-pyridazinoquinazoline-2,10-diones have been prepared by hydrazinolysis of o-alkoxycarbonylsuccinanilic acids (IIIa-d), alkyl o-alkoxycarbonylsuccinanilates (IVa-f) or alkyl β-(4-oxo-3,1-benzoxazin-2-yl)propionates (Va,b) via
