120589-32-4

Upstream product

• 120589-28-8 (S)-N-Boc-4-amino-6-methyl-1-phenyl-1-heptyn-3-one 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 87694-50-6 N-(tert-butoxycarbonyl)-L-leucine-N'-methoxy-N'-methylamide 
• 120589-49-3 (4S,5R)-N-Boc-isobutyl-5-phenylethynyloxazolidin-2-one 
• 4440-01-1 lithium phenylacetylide 
• 120589-44-8 (4S,5R)-isobutyl-5-phenylethynyloxazolidin-2-one 
• 120589-32-4 ((S)-2-Hydroxy-1-isobutyl-4-phenyl-but-3-ynyl)-carbamic acid tert-butyl ester 

Downstream Products

• 120589-42-6 (4S,5S)-isobutyl-5-phenylethynyloxazolidin-2-one 
• 120589-44-8 (4S,5R)-isobutyl-5-phenylethynyloxazolidin-2-one 
• 120589-49-3 (4S,5R)-N-Boc-isobutyl-5-phenylethynyloxazolidin-2-one 

Relevant academic research and scientific papers

A versatile approach to N-Boc-statine and N-Boc-norstatine based on the reduction of 1-trialkylsilyl acetylenic ketones. Strong remote effect of the C(1) substituent on the stereoselectivity

(formula presented) An efficient, unified approach to chiral, protected β-hydroxy γ-amino and α-hydroxy β-amino acids derived from Boc-L-leucine has been accomplished on the basis of the oxazaborolidine-controlled, stereoselective reduction of 1-trialkyls

Diastereoconversion of 1-Alkynyl-2-aminoalkanols through Oxazoline-2-ones with SN2 Type Inversion of the Hydroxy Group

erythro N-Boc-1-Alkynyl-2-amino alcohols were treated with thionyl chloride in ether under ice-cooling to afford the corresponding 4,5-trans-4,5-disubstituted oxazolidin-2-ones which were easily converted to the corresponding threo N-Boc-2-amino alcohols.