1206-69-5

Basic information

• Product Name: 2,4-dihydroxy-6-(2-oxopropyl)benzoic acid
• Synonyms: 2,4-dihydroxy-6-(2-oxopropyl)benzoic acid;2-(2-Oxopropyl)-4,6-dihydroxybenzoic acid;α-Acetylorsellinic acid
• CAS NO: 1206-69-5
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 0
• Mol File: 1206-69-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 435.5°Cat760mmHg
• Flash Point: 231.3°C
• Appearance: /
• Density: 1.446g/cm³
• Vapor Pressure: 2.34E-08mmHg at 25°C
• Refractive Index: 1.621
• CAS DataBase Reference: 2,4-dihydroxy-6-(2-oxopropyl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dihydroxy-6-(2-oxopropyl)benzoic acid(1206-69-5)
• EPA Substance Registry System: 2,4-dihydroxy-6-(2-oxopropyl)benzoic acid(1206-69-5)

Safety Data

• Hazardous Substances Data: 1206-69-5(Hazardous Substances Data)

Usage

General Description

2,4-dihydroxy-6-(2-oxopropyl)benzoic acid, also known as gentisic acid, is a naturally occurring compound found in various fruits and vegetables. It is a derivative of salicylic acid and exhibits antioxidant and anti-inflammatory properties. Gentisic acid has been shown to have potential therapeutic effects in treating various health conditions, including oxidative stress, diabetes, and cardiovascular diseases. Additionally, it has been investigated for its potential use in cosmetic and skincare products due to its ability to protect against oxidative damage and inflammation in the skin. Overall, gentisic acid is a versatile compound with promising applications in both the pharmaceutical and cosmetic industries.

InChI:InChI=1/C10H10O5/c1-5(11)2-6-3-7(12)4-8(13)9(6)10(14)15/h3-4,12-13H,2H2,1H3,(H,14,15)

Downstream Products

• 6512-23-8 2-methoxycarbony;-3-hydroxy-5-methoxybenzyl ketone 
• 1204-37-1 saccharonol A 

Relevant articles and documents

Hansforesters A-M, polyesters from the sponge-associated fungus Hansfordia sinuosae with antibacterial activities

Bioassay-guided fractionation and chromatographic separation of a sponge-derived fungus Hansfordia sinuosae, resulted in the isolation of thirteen new polyesters namely hansforesters A-M (1-13), along with five known analogues involving ascotrichalactone A, ascotrichester B, 15G256π, 6R-hydroxymellein, and (?)orthosporin. The structures of the new compounds were determined through extensive spectroscopic analysis, in addition to the chemical conversion for the configurational assignment. The polyesters incorporating the motifs of orsellinic acid, 2,4-dihydroxy-6-acetonylbenzoic acid, and orcinotriol were found from nature for the first time. Hansforester A (1) and ascotrichalactone A exhibited potent inhibition against a panel of bacterial strains, including the agricultural pathogenic bacteria, Pseudomonas lachrymans, Agrobacterium tumefaciens, Xanthomonas vesicatoria, and Ralstonia solanacearum, with the MIC values of 15.6 μM, and the human infected bacterium Staphylococcus aureus with the MIC values of 3.9 μM. These findings suggested that hansforester A and ascotrichalactone A are the potential leads to be developed as the antibacterial agents for the treatment of agriculture bacterial pathogens.