120607-71-8

Basic information

• Product Name: 1-(5-Bromo-3-phenyl-1H-indole-2-carbonyl)-3-phenyl-1H-pyrazole-4-carbaldehyde
• CAS NO: 120607-71-8
• Molecular Weight: 470.325
• Mol File: 120607-71-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-Bromo-3-phenyl-1H-indole-2-carbonyl)-3-phenyl-1H-pyrazole-4-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-Bromo-3-phenyl-1H-indole-2-carbonyl)-3-phenyl-1H-pyrazole-4-carbaldehyde(120607-71-8)
• EPA Substance Registry System: 1-(5-Bromo-3-phenyl-1H-indole-2-carbonyl)-3-phenyl-1H-pyrazole-4-carbaldehyde(120607-71-8)

Safety Data

• Hazardous Substances Data: 120607-71-8(Hazardous Substances Data)

Upstream product

• 120607-63-8 5-Bromo-3-phenyl-1H-indole-2-carboxylic acid [1-phenyl-eth-(E)-ylidene]-hydrazide 
• 68-12-2 N,N-dimethyl-formamide 
• 98-86-2 acetophenone 
• 70070-24-5 5-bromo-3-phenylindole-2-carboxyhydrazide 

Relevant articles and documents

Synthesis of Various Pyrazole-1-carbonylindoles

Indole-2-carbohydrazides (1a-n) when heated with acetylacetone and ethyl acetoacetate in methanol afford the substituted 2-(3',5'-dimethylpyrazole-1'-carbonyl)indoles (2a-n) and 3-methyl-1(2'-indolyl)-5(4H)-pyrazolones (3e-a), respectively in good yields.The schiff's bases (4a-h) from hydrazides (1a-h) and acetophenone on reaction with POCl3 and DMF produce the substituted 2-(4'-formyl-3'-phenylpyrazole-1'-carbonyl)indoles (5a-h).Indole-3-carboxaldehydes (6a-f) undergo condensation with ethyl cyanoacetate and malononitrile to give the acrylonitriles 7a-f and 9a-e which on reaction with hydrazine hydrate yield 3-amino-5-hydroxy-4-(3'-indolylmethylene)pyrazoles (8a-f) and 3,5-diamino-4-(3'-indolylmethylene)pyrazoles (10a-e), respectively.Similarly indole-2-carboxaldehydes (11a-d) react with ethyl cyanoacetate and hydrazine hydrate to furnish the respective pyrazoles (13a-d).