120609-13-4

Basic information

• Product Name: 1-Bromo-2-phenyl-3-buten-2-ol
• Synonyms: 1-Bromo-2-phenyl-3-buten-2-ol
• CAS NO: 120609-13-4
• Molecular Weight: 227.101
• Mol File: 120609-13-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Bromo-2-phenyl-3-buten-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-phenyl-3-buten-2-ol(120609-13-4)
• EPA Substance Registry System: 1-Bromo-2-phenyl-3-buten-2-ol(120609-13-4)

Safety Data

• Hazardous Substances Data: 120609-13-4(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 1826-67-1 vinyl magnesium bromide 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 1418143-49-3 (2Z)-4-bromo-3-phenyl-2-butenyl acetate 
• 4411-89-6 (E/Z)-2-phenylcrotonaldehyde 
• 97699-36-0 2-phenyl-2-vinyloxirane 

Relevant articles and documents

Systematic Synthesis of Diphenyl-Substituted Carotenoids as Molecular Wires

A general method for the construction of diphenyl-substituted carotenoids has been developed through the stereoselective synthesis of dienyl sulfones with a phenyl substituent. Systematic synthetic pathways to the dienyl sulfones were delineated starting from readily available acetophenones with para-substituent X of various electronic natures, which provided the carotenoids with diverse physicochemical characteristics. The sulfone olefination method together with the Ramberg–B?cklund reaction produced a 9,9′-cis-10,10′-diphenylcarotene and all-trans-9,9′-diphenylcarotenes. Conductance measurements of the all-trans carotenoids by the scanning tunnelling microscopy break-junction method revealed a positional effect of the phenyl groups as well as a polar effect of the phenyl substituent X according to the electronic nature.

2,7-DIPHENYLOCTA-2,4,6-TRIENEDIAL, METHOD FOR PREPARING THE SAME AND METHOD FOR PREPARING CAROTENOIDS CONTAINING PHENYL SUBSTITUENTS USING THE SAME

The present invention relates to an intermediate, a method for synthesizing the same, and a method for efficiently synthesizing a carotene compound containing a phenyl substituent using the same, wherein the intermediate needed to prepare a polyene structure of a carotene compound having a variety of physicochemical and electroelectronic properties according to electronic properties of the phenyl substituent in a single step reaction, and exhibiting improved antioxidant abilities by containing the phenyl substituent. To this end, 2,7-diphenyl-2,4,6-trienedial of chemical formula 1, which is a novel compound, and 2-((3-(5,5-dimethyl-1,3-dioxane-2-yl)-3-phenylallyl)sulfonyl)benzo[d]thiazole of chemical formula 2, and a synthesis method thereof are proposed by an efficient method using a common intermediate. The novel compound can be efficiently used for synthesis of a carotene compound containing various phenyl substituents through a Julia-Kocienski reaction or a Wittig reaction.COPYRIGHT KIPO 2019

Reactions of Carbonyl Compounds with Grignard Reagents in the Presence of Cerium Chloride

The addition of Grignard reagents to ketones is significantly enhanced by cerium chloride with remarkable supression of side reactions, particularly enolization.Some esters, which are prone to side reactions, also react readily with Grignard reagents in the presence of cerium chloride to give normal reaction products in reasonable to high yields.