120629-52-9Relevant academic research and scientific papers
Peptidyl α-Ketoheterocyclic Inhibitors of Human Neutrophil Elastase. 3. In Vitro and in Vivo Potency of a Series of Peptidyl α-Ketobenzoxazoles
Edwards, Philip D.,Zottola, Mark A.,Davis, Matthew,Williams, Joseph,Tuthill, Paul A.
, p. 3972 - 3982 (2007/10/03)
A series of peptidyl α-ketobenzoxazoles were synthesized and evaluated for their in vitro and in vivo inhibition of human neutrophil elastase (HNE).These compounds inhibit HNE by forming both a covalent bond between the ketone carbonyl carbon atom and the
