120633-59-2

Upstream product

• 106267-98-5 (-)-(2S)-2-hydroxy-2-(hydroxymethyl)-2,2'-O-isopropylidenepent-4-enoic acid 
• 100-39-0 benzyl bromide 
• 212763-45-6 (-)-(2R)-2-hydroxy-2-(hydroxymethyl)-2,2'-O-isopropylidenepent-4-enol 

Downstream Products

• 512778-13-1 4-amino-1-[3-(4-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propyl]-1H-pyrimidin-2-one 
• 512778-12-0 9-[3-(4-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propyl]-9H-purin-6-ylamine 
• 120633-61-6 (2R)-2-benzyloxymethyl-1-p-toluenesulfonyloxy-pent-4-ene-2-ol 
• 120633-64-9 (6R)-6-benzyloxymethyl-6-hydroxy-hept-3-ene-(E)-2-one 
• 120633-63-8 (3R)-3-benzyloxymethyl-3-hydroxy-butanal 
• 120633-62-7 (R)-1-benzyloxy-2-methyl-4-pentene-2-ol 
• 512778-11-9 Methanesulfonic acid 3-((R)-4-benzyloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propyl ester 
• 120633-60-5 (2S)-2-hydroxy-2-(benzyloxymethyl)-4-penten-1-ol 

Relevant academic research and scientific papers

Synthesis and anti-HCMV activity of novel acyclic nucleosides

A series of novel acyclic nucleosides 10, 11, 21, and 22 were synthesized efficiently starting from D-lactose. The condensation of the mesylate 5 and 16 with an adenine and cytosine base under standard nucleophilic substitution conditions (K2CO

TOTAL SYNTHESIS OF (S)-(-) AND (R)-(+)-FRONTALIN AND OF (-)-MALYNGOLIDE FROM THE BRANCHED-CHAIN SUGAR "α"-D-ISOSACCHARINO-LACTONE AS CHIRAL TEMPLATE

Highly enantiomerically pure (S)-(-) 2 and (R)-(+)-frontalin 3 and (-)-malyngolide 4 were synthesized from the common chiral building block, (2R)-1,2-O-isopropylidene-2-hydroxymethyl-pent-4-ene-1,2-diol 9 readily prepared in five steps and 35percent overa