1206465-47-5

Basic information

• Product Name: 2-[4-(3-carboxypropionylamino)benzenesulphonylamino]pentanedioic acid
• Synonyms: 2-[4-(3-carboxypropionylamino)benzenesulphonylamino]pentanedioic acid
• CAS NO: 1206465-47-5
• Molecular Weight: 402.382
• Mol File: 1206465-47-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[4-(3-carboxypropionylamino)benzenesulphonylamino]pentanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[4-(3-carboxypropionylamino)benzenesulphonylamino]pentanedioic acid(1206465-47-5)
• EPA Substance Registry System: 2-[4-(3-carboxypropionylamino)benzenesulphonylamino]pentanedioic acid(1206465-47-5)

Safety Data

• Hazardous Substances Data: 1206465-47-5(Hazardous Substances Data)

Upstream product

• 102-14-7 N-phenyl-succinamic acid 
• 56-86-0 L-glutamic acid 
• 40686-14-4 4-(2,5-dioxopyrrolidin-1-yl)benzenesulphonyl chloride 
• 83-25-0 N-phenylmaleimide 

Downstream Products

• 1030617-01-6 1-[4-(2,5-dioxo pyrrolidin-1-yl)benzenesulphonyl]-5-oxopyrrolidin-2-carboxylic acid 
• 1370006-33-9 1-[4-(2,5-dioxopyrrolidine-1-yl)benzenesulphonyl]-5-oxopyrrolidine-2-carboxylic acid amide 
• 1370006-34-0 1-[4-(2,5-dioxopyrrolidin-1-yl)]-5-oxopyrrolidine-2-carboxylic acid methyl amide 
• 1370006-35-1 1-[4-(2,5-dioxopyrrolidin-1-yl)]-5-oxo-pyrrolidine-2-carboxylic acid ethyl amide 
• 1370006-36-2 1-[4-(2,5-dioxopyrrolidin-1-yl)]-5-oxopyrrolidine-2-carboxylic acid phenyl amide 
• 1370006-37-3 {1-[4-(2,5-dioxopyrrolidin-1-yl)]-5-oxopyrrolidine-2-carbonyl}urea 
• 1370006-38-4 1-[4-(2,5-dioxopyrrolidin-1-yl)benzenesulphonyl]-2-(hydrazinocarbonyl)-5-oxopyrrolidine 

Relevant articles and documents

Possible antineoplastic agents, part XVII: Synthesis, antitumor and antiangiogenic study of few bioisosteres of thalidomide metabolites

Two series of bioisostere of thalidomide metabolites and their cyclized variants were designed, synthesized and characterized. In vivo antitumor activity was studied on EAC in swiss albino mice. Cytotoxicity study was carried out on HUVEC and Vero cell lines by MTT assay method. Antiangiogenic activity on Ehrlich ascites tumor (EAT) was investigated studying inhibition of formation of micro vessels by identification of CD31 antigen through immunohistochemistry. One molecule has exhibited both antitumor and antiangiogenic activity but there is no significant toxic effect on normal cell.