1206485-35-9

Upstream product

• 150560-58-0 5-(1-Methylethyl)-1H-indole-2,3-dione 
• 100-39-0 benzyl bromide 

Downstream Products

• 1345837-99-1 (E)-ethyl 2-(1-benzyl-5-isopropyl-2-oxoindolin-3-ylidene)acetate 
• 1345838-25-6 (2'R,3'R)-ethyl 1-benzyl-5-isopropyl-2-oxospiro[indoline-3,2'-oxirane]-3'-carboxylate 
• 1345838-26-7 (2'S,3'R)-ethyl 1-benzyl-5-isopropyl-2-oxospiro[indoline-3,2'-oxirane]-3'-carboxylate 
• 1267807-83-9 diethyl {[(3E)-1-benzyl-5-isopropyl-2-oxoindolin-3-ylidene]methyl}phophonate 
• 1206485-39-3 methyl (2E)-[1-benzyl-2-oxo-5-(propan-2-yl)-1,2-dihydro-3H-indol-3-ylidene]ethanoate 

Relevant academic research and scientific papers

Diastereo- and Enantioselective Synthesis of Borylated 3-Hydroxyoxindoles by Addition of gem-Diborylalkanes to Isatins

The catalytic asymmetric synthesis of borylated 3-hydroxyoxindoles by addition of gem-diborylalkanes to isatins is disclosed. Chiral 3-hydroxyoxindoles bearing two contiguous stereogenic centers were produced in up to >20:1 dr and 99% ee. The synthetic utility of the corresponding products is presented through several transformations of the boryl moiety. This report provides an efficient strategy to incorporate a boryl functional group toward the synthesis of 3-hydroxyoxindoles.