120650-99-9

Upstream product

• 120651-05-0 α-cyano-β-dimethylaminocrotonamide 
• 62-53-3 aniline 

Downstream Products

• 108958-64-1 4-anilino-5-formyl-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 103607-65-4 1-Phenyl-4-oxo-5-cyano-6-(β-dimethylaminovinyl)-1,4-dihydropyrimidine 
• 103607-70-1 3-cyano-4-phenylamino-1,2-dihydropyridin-2-one 

Relevant academic research and scientific papers

Synthesis and hydrolytic cleavage of 1-aryl-5-cyano-6-(2- dimethylaminovinyl)-4-oxo(thioxo)-1,4-dihydropyrimidines

1-Aryl-5-cyano-6-(2-dimethylaminovinyl)-4-oxo-1,4-dihydropyrimidines and their 4-thioxo analogs, which were prepared in three steps from cyanoacetamide and cyanothioacetamide, respectively, were subjected to hydrolysis. In aqueous AcOH, hydrolysis of N-(dimethylaminomethylene)-2-cyano-5-dimethylamino-2,4- pentadieneamide derivatives containing amino groups at position 3 afforded formylpyridones. The reaction of 2-cyano-3-dimethylaminothiocrotonamide with DMF dimethyl acetal gave rise to 3-cyano-4-dimethylamino-2-methylthiopyridine.