120656-45-3Relevant academic research and scientific papers
Synthesis and structure-activity relationship of trimebutine derivatives
Sai, Hiroshi,Ozaki, Yasuhiko,Hayashi, Kimiaki,Onoda, Yuichi,Yamada, Kenji
, p. 1168 - 1173 (2007/10/03)
Trimebutine derivatives were synthesized by utilizing alkylation or acylation of isonitriles and nitrile as a key step. The colonic contractile effects of these compounds were examined, and T-1815 was found to have strong colonic propulsive activity.
