1206641-20-4

Usage

Chemical compound

3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)propan-1-ol
Consists of a propanol group attached to a phenyl group via an oxygen atom
The phenyl group is linked to a boron-containing dioxaborolane ring
Commonly used in organic chemistry as a reagent for synthesizing various organic compounds
Utilized as a building block in the production of pharmaceuticals and agrochemicals
Presence of boron-containing dioxaborolane ring gives unique properties for chemical reactions and processes.

Upstream product

• 67900-64-5 3-(4-Bromophenoxy)-1-propanol 
• 73183-34-3 bis(pinacol)diborane 
• 178905-39-0 3-[1,1-bis(methylethyl)-2-methyl-1-silapropoxy]propane-1-ol 
• 269409-70-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 540-38-5 p-Iodophenol 
• 145073-42-3 3-(4-iodophenoxy)propan-1-ol 

Downstream Products

• 1415309-80-6 C₁₃H₁₅N₃O₃ 
• 1382182-62-8 C₁₆H₂₅BO₆S 
• 1312473-72-5 N-hydroxy-4-(4-(4-(3-hydroxypropoxy)phenyl)-2-oxopyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)butanamide 
• 1312479-02-9 4-(4-(4-(3-hydroxypropoxy)phenyl)-2-oxopyridin-1(2H)-yl)-2-methyl-2-(methylsulfonyl)-N-(tetrahydro-2H-pyran-2-yloxy)butanamide 

Relevant academic research and scientific papers

Catalytic Hydroalkylation of Allenes

We have developed a catalytic method for the hydroalkylation of allenes using alkyl triflates as electrophiles and silane as a hydride source. The reaction has an excellent substrate scope and is compatible with a wide range of functional groups, including esters, aryl halides, aryl boronic esters, sulfonamides, alkyl tosylates, and alkyl bromides. We found evidence for a reaction mechanism that involves unusual dinuclear copper ally complexes as catalytic intermediates. The unusual structure of these complexes provides a rationale for their unexpected reactivity.

ANTIOXIDANT, LIQUID CRYSTAL COMPOSITION, AND DISPLAY ELEMENT

PROBLEM TO BE SOLVED: To provide a compound and a composition giving such properties to a liquid crystal display element that when the liquid crystal display element is irradiated with UV rays, a voltage holding ratio of the display element hardly decreas

Isocytosine-based inhibitors of xanthine oxidase: Design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia

Structure-activity relationship studies were carried out for lead generation following structure-guided design approach from an isocytosine scaffold identified earlier for xanthine oxidase inhibition. A 470-fold improvement in in vitro IC50 was obtained in the process. Five most potent compounds with nanomolar IC50 values were selected for pharmacokinetics and in vivo experiments. The best compound showed good in vivo activity when administered intraperitoneally but was not active by oral route. The results suggest that improvement in oral exposure could improve the in vivo efficacy of this series.

N-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS

The present invention is directed to a new class of hydroxamic acid derivatives, their use as LpxC inhibitors, and more specifically their use to treat bacterial infections. Formula (I).