1206884-53-8

Basic information

• Product Name: 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine
• Synonyms: 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine
• CAS NO: 1206884-53-8
• Molecular Weight: 228.681
• Mol File: 1206884-53-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine(1206884-53-8)
• EPA Substance Registry System: 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine(1206884-53-8)

Safety Data

• Hazardous Substances Data: 1206884-53-8(Hazardous Substances Data)

Upstream product

• 23031-08-5 benzoyl(pyridin-1-ium-1-yl)amide 
• 1085710-25-3 (E)-1-chloro-2-(2-iodovinyl)benzene 
• 110-86-1 pyridine 
• 611-17-6 1-bromomethyl-2-chlorobenzene 
• 25275-41-6 N-iminopyridinium ylide 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 59942-87-9 2-hydroxypyrazolo<1,5-α>pyridine 

Relevant articles and documents

Synthesis of 2-Arylpyrazolo[1,5- a ]pyridines by Suzuki-Miyaura Cross-Coupling Reaction

Convenient access to a variety of 2-arylated pyrazolo[1,5-a]pyridine via pyrazolo[1,5-a]pyridine-2-yl triflate using the Suzuki-MiyauraA AA cross-coupling reaction is described. Fifteen 2-arylpyrazolo[1,5-a]pyridine derivatives were synthesized in 52-95% yields.

Synthesis of 2-Substituted Pyrazolo[1,5-a]pyridines through Cascade Direct Alkenylation/Cyclization Reactions

[Chemical equation presented] The synthesis of 2-substituted pyrazolo[1,5-a]pyridines from N-iminopyridinium ylides is described. These medicinally interesting compounds are formed through a cascade process involving a palladium-catalyzed direct alkenylation reaction followed by silver-mediated cyclization. The reaction can be performed with a wide range of electron-poor and electron-rich alkenyl iodides in good yields. This work represents perhaps the most direct route for the preparation of these compounds.