59942-87-9 Usage
Description
PYRAZOLO[1,5-A]PYRIDIN-2-OL is a heterocyclic chemical compound with the molecular formula C6H6N2O, featuring a fused pyrazole and pyridine ring. As a derivative of pyrazole, it is utilized in medicinal chemistry as a fundamental building block for the synthesis of diverse bioactive compounds. Its potential pharmacological activities include acting as an inhibitor of the enzyme phosphodiesterase 5, as well as exhibiting antimicrobial and antitumor properties. PYRAZOLO[1,5-A]PYRIDIN-2-OL is recognized for its versatility and holds promise for applications in drug development and other research areas.
Uses
Used in Pharmaceutical Industry:
PYRAZOLO[1,5-A]PYRIDIN-2-OL is used as a key intermediate in the synthesis of various pharmaceutical compounds for its potential to contribute to the development of new drugs with diverse therapeutic applications.
Used in Medicinal Chemistry Research:
PYRAZOLO[1,5-A]PYRIDIN-2-OL is utilized as a building block for the creation of bioactive molecules, facilitating the exploration of its pharmacological properties and its role in inhibiting specific enzymes like phosphodiesterase 5.
Used in Antimicrobial Applications:
PYRAZOLO[1,5-A]PYRIDIN-2-OL is studied for its potential antimicrobial properties, serving as a candidate for the development of new antimicrobial agents to combat resistant strains of bacteria.
Used in Antitumor Applications:
PYRAZOLO[1,5-A]PYRIDIN-2-OL is investigated for its antitumor properties, with potential use in the development of cancer treatments that target tumor growth and progression.
Used in Drug Development:
PYRAZOLO[1,5-A]PYRIDIN-2-OL is employed in drug development processes, leveraging its versatility to enhance the discovery and design of novel therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 59942-87-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,9,9,4 and 2 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 59942-87:
(7*5)+(6*9)+(5*9)+(4*4)+(3*2)+(2*8)+(1*7)=179
179 % 10 = 9
So 59942-87-9 is a valid CAS Registry Number.
59942-87-9Relevant articles and documents
In Situ Preparation and Consumption of O -Mesitylsulfonylhydroxylamine (MSH) in Continuous Flow for the Amination of Pyridines
Brocklehurst, Cara E.,Koch, Guido,Rothe-P?llet, Stephanie,La Vecchia, Luigi
supporting information, p. 1636 - 1640 (2017/08/11)
The paper demonstrates a safe method in which highly unstable O -mesitylsulfonylhydroxylamine (MSH) can be prepared and consumed in continuous flow. MSH was prepared in situ and used for the flow amination of a range of pyridines, which were subsequently transformed into useful pyrazolopyridine building blocks.
PYRAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS
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Page/Page column 54, (2013/04/10)
This invention relates to pyrazolopyridyl compounds of the structural formula: [Formula should be inserted here] or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone s
N- and O-substituted aminophenols, method and use for diagnosis
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, (2008/06/13)
The present invention provides N- and O-substituted aminophenol derivatives of the general formula STR1 wherein R1, R2, R3, G and L are as hereinbefore defined. The present invention also provides intermediates for the preparation of these aminophenol derivatives of general formula (I), as well as the use of the aminophenol derivatives of general formula (I) for the determination of hydrolyses, as well as for the preparation of agents for carrying out determinations of hydrolyses.
