59942-87-9

Basic information

• Product Name: PYRAZOLO[1,5-A]PYRIDIN-2-OL
• Synonyms: PYRAZOLO[1,5-A]PYRIDIN-2-OL;Pyrazolo[1,5-a]pyridin-2(1H)-one;2-hydroxypyrazolo[1,5-a]pyridine;Pyrazolo[1,5-a]pyridin-2(1H)
• CAS NO: 59942-87-9
• Molecular Formula: C₇H₆N₂O
• Molecular Weight: 134.14
• Mol File: 59942-87-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 127-128 °C(Solv: hexane (110-54-3); benzene (71-43-2))
• Appearance: /
• Density: 1.36
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 10.08±0.20(Predicted)
• CAS DataBase Reference: PYRAZOLO[1,5-A]PYRIDIN-2-OL(CAS DataBase Reference)
• NIST Chemistry Reference: PYRAZOLO[1,5-A]PYRIDIN-2-OL(59942-87-9)
• EPA Substance Registry System: PYRAZOLO[1,5-A]PYRIDIN-2-OL(59942-87-9)

Safety Data

• Hazardous Substances Data: 59942-87-9(Hazardous Substances Data)

Usage

General Description

PYRAZOLO[1,5-A]PYRIDIN-2-OL is a chemical compound with the molecular formula C6H6N2O. It is a heterocyclic compound with a fused pyrazole and pyridine ring. PYRAZOLO[1,5-A]PYRIDIN-2-OL is a derivative of pyrazole and is used in medicinal chemistry as a building block for the synthesis of various bioactive compounds. It has been studied for its potential pharmacological activities, including its role as an inhibitor of the enzyme phosphodiesterase 5. Additionally, it has been investigated for its potential antimicrobial and antitumor properties. PYRAZOLO[1,5-A]PYRIDIN-2-OL has shown promise as a versatile chemical with potential applications in drug development and other fields of research.

Upstream product

• 1658-42-0 methyl 2-pyridylacetate 
• 2739-98-2 ethyl 2-(pyridinyl-2)acetate 
• 497-19-8 sodium carbonate 

Downstream Products

• 1428432-94-3 2-chloro-3-phenylpyrazolo[1,5-a]pyridine 
• 1428432-79-4 2-(5-fluoropyridin-3-yl)-3-phenylpyrazolo[1,5-a]pyridine 
• 60637-33-4 2-chloropyrazolo[1,5-a]pyridine 
• 1428432-86-3 2-chloro-3-cyclopropylpyrazolo[1,5-a]pyridine 
• 1428432-88-5 2-chloro-3-methylpyrazolo[1,5-a]pyridine 
• 80537-14-0 ethyl pyrazolo<1,5-a>pyridine-2-carboxylate 
• 1206884-53-8 2-(2-chlorophenyl)pyrazolo[1,5-a]pyridine 
• 36751-44-7 2-(4-chlorophenyl)pyrazolo[1,5-a]pyridine 
• 56983-95-0 2-phenylpyrazolo[1,5-a]pyridine 
• 1060725-95-2 2-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}pyrazolo[1,5-a]pyridine-3-carbaldehyde 
• 1060725-14-5 2-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}pyrazolo[1,5-a]pyridine 
• 1451182-01-6 1-benzyl-N-methyl-N-(4-(pyrazolo[1,5-a]pyridin-2-yloxy)butyl)piperidin-4-amine 
• 1451184-45-4 3-chloro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-2-ol 

Relevant articles and documents

In Situ Preparation and Consumption of O -Mesitylsulfonylhydroxylamine (MSH) in Continuous Flow for the Amination of Pyridines

The paper demonstrates a safe method in which highly unstable O -mesitylsulfonylhydroxylamine (MSH) can be prepared and consumed in continuous flow. MSH was prepared in situ and used for the flow amination of a range of pyridines, which were subsequently transformed into useful pyrazolopyridine building blocks.

PYRAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS

This invention relates to pyrazolopyridyl compounds of the structural formula: [Formula should be inserted here] or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone s

N- and O-substituted aminophenols, method and use for diagnosis

The present invention provides N- and O-substituted aminophenol derivatives of the general formula STR1 wherein R1, R2, R3, G and L are as hereinbefore defined. The present invention also provides intermediates for the preparation of these aminophenol derivatives of general formula (I), as well as the use of the aminophenol derivatives of general formula (I) for the determination of hydrolyses, as well as for the preparation of agents for carrying out determinations of hydrolyses.