120692-35-5Relevant academic research and scientific papers
The first titanocenyl dichloride moiety vectorised by a selective estrogen receptor modulator (SERM). Synthesis and preliminary biochemical behaviour
Top,Kaloun,Vessières,Laos,Leclercq,Jaouen
, p. 350 - 356 (2002)
The synthesis of 4′, a titanocene derivative of the anticancer drug tamoxifen is presented together with its biochemical properties. Compound 4′ is prepared by a McMurry coupling followed by a ligand exchange. Compound 4′ reveals an unexpected proliferative effect on the hormone-dependent cell line MCF7. Surprisingly this effect is also observed with Cp2TiCl2 alone.
Crystal Structure and Conformational Analysis of N,N-Dimethyl-N--N-n-dodecyl-ammonium Bromide: Molecule Acting as UV Filter
Anselmi, Cecilia,Centini, Marisanna,Scotton, Mirella,Sega, A.,Dapporto, P.,Paoli, P.
, p. 126 - 130 (1992)
The solid state conformation of the title compound was determined.Conformational analysis based on molecular modelling mechanics allowed the calculation of the energy of the most stable conformers and their comparison with X-ray conformation.
