1207-59-6

Basic information

• Product Name: 2,5-Dimethoxy-4-nitrobenzaldehyde
• Synonyms: 2,5-Dimethoxy-4-nitrobenzaldehyde
• CAS NO: 1207-59-6
• Molecular Formula: C₉H₉NO₅
• Molecular Weight: 211.17146
• Mol File: 1207-59-6.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Dimethoxy-4-nitrobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Dimethoxy-4-nitrobenzaldehyde(1207-59-6)
• EPA Substance Registry System: 2,5-Dimethoxy-4-nitrobenzaldehyde(1207-59-6)

Safety Data

• Hazardous Substances Data: 1207-59-6(Hazardous Substances Data)

Usage

Derived from

Benzaldehyde

Substituents

Two methoxy and one nitro group on the benzene ring

Usage

Organic synthesis, medicinal chemistry (building block for synthesis of pharmaceuticals and fine chemicals), reagent in preparation of other compounds, chemical intermediate in production of dyes and pigments

Biological activities

Antioxidant, anticancer agent

Upstream product

• 93-02-7 2,5-dimethoxybenzaldehyde 
• 143536-20-3 2,5-dimethoxy-4-nitrobenzaldehyde diacetate 
• 55669-73-3 1,1-diacetoxy-1-(2,5-dimethoxyphenyl)methane 

Downstream Products

• 1568-70-3 4-methoxy-2-nitrophenol 

Relevant articles and documents

SMALL MOLECULE INDUCERS OF REACTIVE OXYGEN SPECIES AND INHIBITORS OF MITOCHONDRIAL ACTIVITY

This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazolinedione structure which function as reactive oxygen species (ROS) inducers and inhibitors of mitochondrial activity within cancer cells (e.g., pancreatic cancer cells), and their use as therapeutics for the treatment of cancer (e.g., pancreatic cancer) and other diseases.

Synthesis and adrenolytic activity of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxy phenoxy)ethylamino)propan-2-ol analogs and its enantiomers. Part 2

The synthesis of (2RS)-1-(5-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol and (2RS)-1-(7-methoxy-1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol and its enantiomers, analogs of 1-(1H-indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol ((RS)-9) is described. Compounds were tested for electrographic, antiarrhythmic, hypotensive and spasmolytic activities as well as for α1-, α2- and β1-adrenoceptors binding affinities. The antagonist potency of the new compounds was compared with carvedilol and (RS)-9.

Synthesis of hipposudoric and norhipposudoric acids: The pigments responsible for the color reaction of the red sweat of Hippopotamus amphibius

Highly unstable pigments, hipposudoric acid and norhipposudoric acid, isolated from the red sweat of hippopotamus were synthesized using the Pschorr reaction for the construction of the fluorene nucleus as the key step and the careful oxidation in the las