1207093-43-3Relevant articles and documents
Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines
Bandi, Vijayalakshmi,Kavala, Veerababurao,Hsu, Che-Hao,Konala, Ashok,Villuri, Bharath Kumar,Kotipalli, Trimurtulu,Kuo, Chun-Wei,Yao, Ching-Fa
, p. 46704 - 46712 (2017)
An approach for the synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives is reported starting from β-halo styrene and phenyl acetylene derivatives in the presence of PdCl2 and CuI catalysts. Functional groups such as aldehyde, cyano and ester groups are well tolerated and afford the desired functionalized dienynes. Further, these 1,3-buta-diene-3-yne derivatives are utilized for the synthesis of novel trisubstituted pyridine derivatives.
Synthesis of novel ferrocenated enynes via the Sonogashira coupling of ferrocenated vinyllic chlorides and alkyne in the catalytic presence of selenated NHC-Pd(II) full pincer complex under Cu and amine free aerobic conditions
Joshi, Raj K.,Nemiwal, Meena,Sharma, Charu,Tomar, Vijesh
supporting information, (2021/10/27)
Herein, a copper free, selenated NHC-Pd(II) full pincer catalyzed Sonogashira cross coupling reaction of ferrocene/phenyl substituted β-chloro-cinnamaldehyde/acrylo-nitrilesmalononitrile has been established for the synthesis of novel ferrocenated enynes at feasible reaction condition. 0.002 mol % of the selenated NHC-Pd(II) pincer complex was found to be highly efficient to couple various substituted acetylenes with β-chloro-cinnamaldehyde/acrylonitriles/malononitrile in just 5 h under the areobic conditions. A library of 26 new ferrocene substituted enyne derivatives has been developed through the present Sonogashira reaction. Electrochemical response for some selective compounds was also investigated.
Gold(i) catalysed sequential dehydrative cyclisation/intermolecular [4 + 2] cycloaddition of alkynyldienols onto activated alkynes/alkenes: a facile route to substituted norbornadienes/norbornenes
Uruvakili, Anasuyamma,Gangadhararao,Kumara Swamy
, p. 10060 - 10071 (2015/10/12)
One-pot synthesis of highly substituted norbornadienes/norbornenes via gold-catalysed dehydrative cyclisation of alkynyldienols, followed by intermolecular [4 + 2] cycloaddition of in situ generated cyclopentadiene and activated alkynes/alkenes is described. The precursors, alkynyldienols, are obtained via sequential Sonogashira cross-coupling of 3-bromoenals, alkyne addition and reduction. Yields of the enynals and multisubstituted norbornadienes in all the cases are good to excellent.
Copper catalyzed synthesis of highly substituted pyrrole and isoindole derivatives
Nandi, Sukla,Ray, Jayanta K.
scheme or table, p. 6203 - 6206 (2011/11/29)
We have developed an efficient synthesis of highly substituted pyrrole and isoindole derivatives using copper(I) catalyst. This methodology is helpful for the synthesis of some quinones bearing annealed N-heterocyclic natural products.
Copper-catalyzed addition of water affording highly substituted furan and unusual formation of naphthofuran ring from 3-(1-alkenyl)-2-alkene-1-al
Jana, Rathin,Paul, Sunanda,Biswas, Anup,Ray, Jayanta K.
supporting information; experimental part, p. 273 - 276 (2010/03/26)
We have developed a novel one-pot reaction to generate highly substituted furan through the addition of water followed by oxidation and unusual cyclization to naphthofuran ring under the same reaction condition.
