120710-98-7

Upstream product

• 532-65-0 (+)-(S)-ar-turmerone 
• 122091-54-7 (R)-(+)-2-(4-methylphenyl)propanol 
• 1178560-59-2 (7S)-bisacumol acetate 
• 127214-85-1 bisacurone B 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 503543-30-4 (R)-1-(1-bromopropan-2-yl)-4-methylbenzene 

Downstream Products

• 1214287-50-9 (+)-(7S,9S)-dihydro-ar-turmerol 
• 1214287-51-0 (+)-(7S,9R)-dihydro-ar-turmerol 
• 4179-21-9 (+)-(S)-dihydro-ar-curcumene 
• 532-65-0 (+)-(S)-ar-turmerone 
• 120681-86-9 4-Bromo-benzoic acid (S)-3-methyl-1-((S)-2-p-tolyl-propyl)-but-2-enyl ester 
• 120681-85-8 4-Bromo-benzoic acid (R)-3-methyl-1-((S)-2-p-tolyl-propyl)-but-2-enyl ester 

Relevant academic research and scientific papers

Acetylcholinesterase inhibitory activity of volatile oil from peltophorum dasyrachis kurz ex bakar (Yellow Batai) and bisabolane-type sesquiterpenoids

In this study, the chemical compositions and acetylcholinesterase (AChE) inhibitory activitiy of the volatile oil from the bark of Peltophorum dasyrachis Kurz ex Bakar (yellow batai) were evaluated. As a result, 68 compounds, accounting for 88.0% of the t

Total synthesis of (R)- and (S)-turmerone and (7S,9R)-bisacumol by an efficient chemoenzymatic approach

An enantioselective synthesis of (R)-, (S)-turmerone and (7S,9R)-bisacumol is described. The enantiomerically pure key intermediates, a substituted butanoate ester and acid are utilized in the synthesis of both enantiomers of turmerone. The lipase catalyzed resolution studies of the acetate of bisacumol have been exploited towards the total synthesis of the naturally occurring cytotoxic sesquiterpene, (7S,9R)-bisacumol with high diastereoselectivity (94% de).

Total asymmetric synthesis of (7S,9R)-(+)-bisacumol

A facile stereoselective synthetic route to (7S,9R)-(+)-bisacumol 1 has been achieved. This novel approach derives its asymmetry by employing asymmetric dihydroxylation and CBS reduction processes. The resulting sesquiterpene 1 was produced with highly enantio- and diastereoselectivity.

NEW BISABOLANE SESQUITERPENOIDS FROM THE RHIZOMES OF CURCUMA XANTHORRHIZA (ZINGIBERACEAE)

Three new bisabolane sesquiterpenoids, bisacurone (1), bisacumol (2) and bisacurol (3), and one known compound, curlone (4), were isolated from the rhizomes of Curcuma xanthorrhiza (Zingiberaceae).The absolute structures of these new compounds were determined by spectroscopy, chemical conversions and the exciton chirality method for allylic alcohols. KEYWORDS - Curcuma xanthorrhiza; Zingiberaceae; bisabolane sesquiterpenoid; bisacurone; bisacumol, bisacurol; curlone; CD; exciton chirality method; allylic alcohol