1207295-77-9

Upstream product

• 22273-77-4 (E)-2-(4-(benzyloxy)but-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 107-18-6 allyl alcohol 
• 1227858-63-0 (E)-2-(4-benzyloxy-but-1-enyl)-[1,3,2]dioxaborinane 
• 181036-38-4 (E)-2-(4-(benzyloxy)but-1-enyl)benzo[d][1,3,2]dioxaborole 
• 185453-07-0 (E)-4-(benzyloxy)but-1-enylboronic acid 

Relevant academic research and scientific papers

Alkoxydienes via copper-promoted couplings: Utilizing an alkyne effect

Simple alkenes and alkynes, with 3-hexyne in particular, are found to be important π ligands for oxidative copper-based coupling (modern Ullmann) reactions. This enabled syntheses of various alkoxydienes with removable protecting groups that are valuable substrates for Diels-Alder reactions from alcohols and vinyl boronate esters. In addition to demonstrating that 3-hexyne is a ligand for copper in both stoichiometric and catalytic reactions, the reaction atmosphere was found to play a critical role.