1207338-56-4Relevant academic research and scientific papers
Diarylprolinol silyl ether catalyzed asymmetric friedel-crafts alkylation of indoles with α,β-unsaturated aldehydes: Enhanced enantioselectivity and mechanistic investigations
Shi, Zi-Hui,Sheng, Hao,Yang, Ke-Fang,Jiang, Jian-Xiong,Lai, Guo-Qiao,Lu, Yixin,Xu, Li-Wen
supporting information; experimental part, p. 66 - 70 (2011/03/18)
A highly enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated aldehydes with excellent enantioselectivities (up to >99%ee) has been developed, and this improved method offers substantial advantages over traditional approaches, not on
Enantioselective friedel-crafts alkylation of indoles with aromatic αβ-unsaturated aldehydes catalyzed by diphenylprolinol silyl Ether
Wang, Zhi-Jing,Yang, Jian-Guo,Jin, Jun,Lv, Xin,Bao, Weiliang
experimental part, p. 3994 - 4000 (2010/03/24)
A catalytic enantioselective Friedel-Crafts alkylation of indoles with aromatic α,β-unsaturated aldehydes has been developed. The process is promoted by (S)-diphenylprolinol trimethyl silyl ether to afford, after sodium borohydride mediated reduction, 3in
