1207376-83-7Relevant academic research and scientific papers
Unexpected high regiocontrol in Heck reaction of fluorine-containing electron-deficient olefins-Highly regio- and stereoselective synthesis of β-fluoroalkyl-α-aryl-α,β-unsaturated ketones
Konno, Tsutomu,Yamada, Shigeyuki,Tani, Akinori,Nishida, Masataka,Miyabe, Tomotsugu,Ishihara, Takashi
experimental part, p. 913 - 921 (2010/01/15)
Treatment of (E)-4,4,4-trifluoro-1-aryl-2-buten-1-one with various aryldiazonium salts in the presence of palladium catalyst gave the corresponding α-arylated Heck adducts with high regio- and stereoselectivity in good to high yields.
