801289-34-9Relevant academic research and scientific papers
Application of Mitsunobu reagents to redox Isomerization of CF 3-containing propargylic alcohols to (E)-α,β-enones
Watanabe, Yohsuke,Yamazaki, Takashi
supporting information; experimental part, p. 1957 - 1960 (2011/06/20)
Isomerization of CF3-containing secondary propargylic alcohols proceeds with excellent E selectivity by treatment with Mitsunobu reagents, tris- (p-methoxyphenyl)phosphine (TMPP), and 1,1′-(azodicarbonyl) dipiperidine (ADDP) in the presence of phenol.
Electronically promoted Payne rearrangement of 3-CF3-2,3- epoxyalcohols
Yamazaki, Takashi,Ichige, Tatsuro,Kitazume, Tomoya
, p. 4073 - 4076 (2007/10/03)
(Chemical Equation Presented) Smooth and selective Payne rearrangement was achieved for the above types of epoxyalcohols with a CF3 group so as to form thermodynamically more stable alkoxides, where the strongly electron-withdrawing nature of this moiety played a significantly important role and was proved to overcome increased steric instability of epoxides from syn-E to anti-Z isomers.
