1207454-86-1

Basic information

• Product Name: 2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-Quinolinecarboxylic acid ethyl ester
• Synonyms: 2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-Quinolinecarboxylic acid ethyl ester
• CAS NO: 1207454-86-1
• Molecular Weight: 409.872
• Mol File: 1207454-86-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-Quinolinecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-Quinolinecarboxylic acid ethyl ester(1207454-86-1)
• EPA Substance Registry System: 2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-Quinolinecarboxylic acid ethyl ester(1207454-86-1)

Safety Data

• Hazardous Substances Data: 1207454-86-1(Hazardous Substances Data)

Usage

Molecular Structure

2-(4-chlorophenyl)-1,2,3,4-tetrahydro-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-5-quinolinecarboxylic acid ethyl ester

Classification

Synthetic quinolone antibiotic

Derivation

Derived from the parent compound ciprofloxacin

Uses

Treats various bacterial infections, including respiratory, urinary tract, skin, and sexually transmitted infections

Mechanism of Action

Inhibits DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, resulting in bactericidal activity against susceptible organisms

Administration

Available in oral and intravenous forms

Safety

Typically well-tolerated with a low risk of adverse effects when used as directed by a healthcare professional

Upstream product

• 65399-18-0 4-nitrophthalide 
• 59434-19-4 4-Amino-1(3H)-isobenzofuranon 
• 1207454-85-0 (E)-4-(4-chlorobenzylideneamino)isobenzofuran-1(3H)-one 
• 141-52-6 sodium ethanolate 
• 105-37-3 Ethyl propionate 
• 13750-81-7 N-methyl-2-imidazolcarboxaldehyde 
• 641-70-3 3-nitrophthalic acid anhydride 

Downstream Products

• 1207454-84-9 8-(4-chlorophenyl)-9-(1-methyl-1H-imidazol-2-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one 

Relevant articles and documents

METHODS OF USING DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY (ADP-RIBOSE)POLYMERASE (PARP)

Provided herein are methods of treating cancer comprising administering a topoisomerase inhibitor, temozolomide, or a platin in combination with a Compound of Formula (I) or Formula (II), where the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein.