1207463-12-4Relevant academic research and scientific papers
Concise synthesis of (2S,3R)-3-hydroxy-2-phenylpiperidine: An advanced key intermediate of human non-peptide NK-1 receptor antagonists
Helal, Benoit,Ferreira, Franck,Botuha, Candice,Chemla, Fabrice,Perez-Luna, Alejandro
, p. 3115 - 3118 (2009)
The rapid, high-yielding synthesis of (25,3R)-3-hydroxy-2-phenylpiperidine, a known advanced key intermediate of some non-peptide human NK-1 receptor antagonists such as (+)CP-99,994, (+)-CP-122,721 and (+)-LP-733,060, is reported. This synthesis involves
