1207477-72-2Relevant academic research and scientific papers
Enantioselective Michael addition of malonates to α,β-unsaturated ketones catalyzed by 1,2-diphenylethanediamine
Wang, Wei,Ye, Ling,Shi, Zhichuan,Zhao, Zhigang,Li, Xuefeng
, p. 41699 - 41704 (2019/01/03)
A general and highly enantioselective Michael addition of malonates to cinnamones and chalcones has been developed. The commercially available 1,2-diphenylethanediamine could be directly utilized as the organocatalyst to furnish the desired adducts in satisfactory yield (61-99%) and moderate to excellent enantiopurity (65 to >99% ee). β-Ketoester was also a competent donor and was employed to construct densely functionalized cyclohexenones via a tandem Michael-aldol condensation process.
Chiral primary-secondary diamines catalyzed michael-aldol-dehydration reaction between benzoylacetates and α,β-unsaturated ketones: Highly enantioselective synthesis of functioned chiral cyclohexenonfs
Yang, Ying-Quan,Chai, Zhuo,Wang, Hai-Feng,Chen, Xing-Kuan,Cui, Hai-Feng,Zheng, Chang-Wu,Xiao, Hua,Li, Peng,Zhao, Gang
supporting information; experimental part, p. 13295-13298+13273 (2010/06/15)
"Chemical Equation Presented" A highly enantioselective organocatalytic tandem Michael-aldol-dehydration reaction that provides an expedited access to highly functionalized chiral cyclohexenone derivatives (such as that depicted) by using a simple diamine
